Anesthesia: Essays and Researches  Login  | Users Online: 335 Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Home | About us | Editorial board | Ahead of print | Search | Current Issue | Archives | Submit article | Instructions | Copyright form | Subscribe | Advertise | Contacts
Year : 2019  |  Volume : 13  |  Issue : 2  |  Page : 225-228

Efficacy of intra-articular dexmedetomidine versus buprenorphine for postoperative analgesia following knee arthroscopy: A comparative study

1 Department of Orthopaedics, IMS and SUM Hospital, Bhubaneswar, Odisha, India
2 Department of Anaesthesiology and Critical Care, IMS and SUM Hospital, Bhubaneswar, Odisha, India

Correspondence Address:
Soumya Samal
B 206, Palm heights, Sampur, Bhubaneswar - 751 003, Odisha
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/aer.AER_33_19

Rights and Permissions

Background: Arthroscopic knee surgery is most commonly performed minimally invasive surgical procedure in orthopaedics. Postoperative pain relief is must for early mobilisation that reduces patient's morbidity and improves postoperative recovery. Aims and Objectives: We sought to compare analgesic efficacy of intraarticular buprenorphine with dexmedetomidine following arthroscopic surgery of knee. Settings and Design: A prospective , randomized controlled double blinded study was conducted involving 60 patients undergoing arthroscopic knee surgery. Materials and Methods: Patients were allocated into group B (n = 30) and group D (n = 30) receiving 100 μg of intraarticular buprenorphine and 100 μg 0f intraarticular dexmedetomidine respectively. Parameters observed were the time to first rescue analgesia , the number of patients requiring rescue analgesia with in next 24 hours, Visual analogue scale (VAS) at rest and on mobilization at 1st, 2nd, 4th, 8th, 12th and 24th hour. Statistical Analysis: Quantitative data were analyzed by unpaired student's t test and categorical data by Fisher's exact test. A P < 0.05 was considered to be significant. Statistical analysis was done using Statistical Package for the Social Sciences (SPSS 19.0, SPSS Inc., Chicago, IL, USA). Results: Time to first rescue analgesia was significantly longer in patients receiving in group B. VAS scores at rest were comparable between the groups at 1st, 2nd, 4th and 8th hour but significantly low with intraarticular buprenorphine than intraarticular dexmedetomidine at 12th and 24th hour. VAS scores on ambulation were comparable at 1st, 2nd and 4th hour but significantly higher in dexmedetomidine group as compared to buprenorphine at 8th, 12th and 24th hour. Conclusion: Intraarticular buprenorphine 100 μg provides longer duration of analgesia with decreased postoperative rescue analgesic requirement as compared to 100 μg intraarticular dexmedetomidine.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded71    
    Comments [Add]    

Recommend this journal