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ORIGINAL ARTICLE
Year : 2019  |  Volume : 13  |  Issue : 2  |  Page : 389-394

A comparative clinical study between clonidine and tramadol with bupivacaine in caudal epidural for postoperative analgesia in pediatric surgery


1 Department of Anaesthesiology, Kodagu Institute of Medical Sciences, Kodagu, Karnataka, India
2 Department of Anaesthesiology, Sakra World Hospital, Bangalore, Karnataka, India
3 Department of Anaesthesiology, M.S. Ramaiah Medical College, Bangalore, Karnataka, India
4 Department of Anaesthesiology, BGS Global Institute of Medical Sciences, Bangalore, Karnataka, India

Correspondence Address:
Thejeswini Mahadevaiah
Department of Anaesthesiology, M.S. Ramaiah Medical College, Bangalore, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/aer.AER_37_19

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Context: Adjuvants to bupivacaine for single shot caudal block in children. Aims: This study entitled was conducted to compare the effects of addition of tramadol to bupivacaine over addition of clonidine to bupivacaine as a single shot caudal block in children. Settings and Design: Sixty children of ASA grade I and II in the age group of 2-12 years coming for various infra-umbilical surgeries were included. Materials and Methods: They were divided into two groups of 30 each. Group BC received caudal bupivacaine 0.25% 0.5ml/kg with clonidine 2 mcg/kg Group BT received caudal bupivacaine 0.25% 0.5 ml/kg with tramadol 2 mg/kg. The main parameters studied were hemodynamic changes, duration of post-operative analgesia and incidence of adverse effects. Statistical Analysis Used: The results of continuous variables are given as mean ± SD and proportion as percentage. The difference between the two groups was assessed by student's – t test and chi-square test Results: The mean duration of post-operative analgesia in group BT was statistically significant (P<0.001), reducing the requirement of analgesics in group BT. There was no difference in sedation score, nausea, vomiting, urinary retention between the two groups. Conclusions: The present study demonstrated that caudal administration of bupivacaine 0.25% 0.5 ml/kg with tramadol 2 mg/kg resulted in superior analgesia with longer duration of action and reduced requirement of analgesics in first 24 hours postoperatively when compared with 0.25% bupivacaine 0.5 ml/kg with clonidine 2 mcg/kg.


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