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Year : 2019  |  Volume : 13  |  Issue : 4  |  Page : 615-619

Ultrasound-guided subclavian perivascular brachial plexus block using 0.5% bupivacaine with dexmedetomidine as an adjuvant: A prospective randomized controlled trial

Department of Anaesthesia, Mediciti Institute of Medical Sciences, Hyderabad, Telangana, India

Correspondence Address:
Ramachandra R Avula
Department of Anaesthesia, Mediciti Institute of Medical Sciences, Ghanpur, Medchal Mandal, R.R. District, Hyderabad - 501 401, Telangana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/aer.AER_122_19

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Background: Ultrasound guidance has dramatically improved the accuracy of nerve localization, and various adjuvants prolong the block and extend analgesia. Aims: This study aimed to evaluate the effects of dexmedetomidine added to 0.5% bupivacaine on the onset and duration of motor and sensory blockade and the duration of analgesia. Settings and Design: This is a prospective, randomized double-blind, study. Materials and Methods: Sixty adult patients aged 20–60 years of either sex undergoing orthopedic procedures on the forearm were randomly allocated into two groups of thirty each: Group BS (bupivacaine + saline) and Group BD (bupivacaine + dexmedetomidine). All patients were administered subclavian perivascular brachial plexus block under ultrasound guidance. Group BS: Patients in this group were administered 20-mL 0.5% bupivacaine + 0.75-mL saline. Group BD: Patients in this group were administered 20-mL 0.5% bupivacaine + 0.75-mL dexmedetomidine (75 μg). Statistical Analysis: Statistical analysis was performed with IBM SPSS software Version 21.0. Quantitative data were expressed as mean ± standard deviation. Independent sample t-test was used for comparisons between the two groups. P < 0.05 was considered statistically significant. Results: Demographic data and surgical characteristics were similar in both groups. The onset times for sensory and motor blocks were statistically significantly shorter in Group BD compared to Group BS (P < 0.01), whereas the duration of blocks and analgesia were statistically significantly longer (P < 0.01) in Group BD. Conclusion: The addition of dexmedetomidine to 0.5% bupivacaine for supraclavicular brachial plexus block shortens the onset time and prolongs both the duration of the block and analgesia.

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