Anesthesia: Essays and Researches

ORIGINAL ARTICLE
Year
: 2019  |  Volume : 13  |  Issue : 1  |  Page : 1--6

Peritubal infiltration of fentanyl compared to dexmedetomidine with ropivacaine in percutaneous nephrolithotomy: A randomized comparative analysis


Sumit Soni1, Kalpesh Parmar2, Shyam Meena Charan1, Sameer Sethi1, Naveen B Naik1 
1 Department of Anaesthesia and Intensive Care, PGIMER, Chandigarh, India
2 Department of Urology, PGIMER, Chandigarh, India

Correspondence Address:
Shyam Meena Charan
Department of Anaesthesia and Intensive Care, PGIMER, Chandigarh
India

Context: Dexmedetomidine has been found as an effective adjuvant in various nerve blocks. Despite several studies on dexmedetomidine with ropivacaine, there is no study on comparing with fentanyl in peritubal infiltration in percutaneous nephrolithotomy (PCNL). Aims: The aim of this study was to compare the effect of the addition of dexmedetomidine or fentanyl in peritubal local anesthetic infiltration on pain scores and analgesic consumption in patients who underwent PCNL. Settings and Design: This was a prospective, randomized, double-blind, tertiary care center-based study. Subjects and Methods: A total of 60 American Society of Anesthesiologists Class I, II, and III patients were selected and randomly divided into two groups: Group RF ropivacaine and fentanyl (n = 30) and Group RD ropivacaine and dexmedetomidine (n = 30). Balanced general anesthesia was given. After completion of the surgery, peritubal infiltration was given at 6 and 12 O'clock positions under fluoroscopic guidance. Postoperative pain was assessed using the visual analog scale and dynamic visual analog scale rating 0–10 for initial 48 h. Postoperative sedation was assessed using five-point sedation score. Time to first rescue analgesic, number of doses of tramadol, and total consumption of tramadol required in 48 h were noted. Statistical Analysis Used: Descriptive data were expressed in mean and standard deviation for between-group comparisons; the Chi-square and Fisher's exact tests were used for categorical variables, whereas t-test and Mann–Whitney U-test were used to compare continuous variables between two groups. Results: Duration of analgesia in group RD (12.87 ± 3.85) is more prolonged than group RF (8.13 ± 3.28) h. Total dose of rescue analgesia required in 48 h in group RF was higher as compared to group RD. Conclusions: Addition of dexmedetomidine to ropivacaine is more effective than fentanyl in terms of prolongation of analgesic efficacy of local anesthetic in peritubal block along with short-lived mild sedation.


How to cite this article:
Soni S, Parmar K, Charan SM, Sethi S, Naik NB. Peritubal infiltration of fentanyl compared to dexmedetomidine with ropivacaine in percutaneous nephrolithotomy: A randomized comparative analysis.Anesth Essays Res 2019;13:1-6


How to cite this URL:
Soni S, Parmar K, Charan SM, Sethi S, Naik NB. Peritubal infiltration of fentanyl compared to dexmedetomidine with ropivacaine in percutaneous nephrolithotomy: A randomized comparative analysis. Anesth Essays Res [serial online] 2019 [cited 2019 Aug 23 ];13:1-6
Available from: http://www.aeronline.org/article.asp?issn=0259-1162;year=2019;volume=13;issue=1;spage=1;epage=6;aulast=Soni;type=0